The study, which tested the effect of a typical daily dose of paracetamol on testosterone production in mice, found there was no effect on testosterone production following 24 hours of paracetamol treatment. However, after seven days of exposure, the amount of testosterone was reduced by 45%.
Commenting on the research findings, the RCM’s Head of Education Carmel Lloyd said; “If women do take medicines such as paracetamol when they are pregnant, they should use the lowest effective dose for the shortest possible time. If the recommended dose doesn’t control their symptoms or they are often in pain, they should seek more advice from their midwife or doctor”.
“Ideally, women should avoid taking medicines when they are pregnant, particularly during the first three months. Minor conditions such as colds or minor aches and pains often do not need treating with medicines. If women feel they need to take medicines such as paracetamol when they are pregnant, they should talk to their midwife or doctor first; they can also get advice from their local pharmacy.”
The research findings are published in the journal Science Translational Medicine http://stm.sciencemag.org/content/7/288/288ra80. To read in more detail the RCM’s response click here.
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