Estimates of the burden of group B Streptococcal disease worldwide for pregnant women, stillbirths, and children.
Clinical Infectious Diseases, volume 65, issue suppl_2, 6 November 2017, pages S200–S219, https://doi.org/10.1093/cid/cix664
Published: 06 November 2017
The first comprehensive estimate of the burden of group B Streptococcus (GBS) has been produced by a team of leading researchers. The largely UK-conducted study aimed to identify estimated exposure to maternal GBS colonization, cases of infant invasive GBS disease, deaths, and disabilities.
GBS is established as a leading cause of infant disease, particularly in the first week after birth. This fact is further supported by the study which estimates that 205000 (uncertainty range, 101000–327000) neonates suffer from early onset group B strep (EOGBS) worldwide and that up to 3.5 million preterm births could be attributable to maternal GBS infection/colonization. An effective maternal vaccine could potentially reduce disease in the mother, the fetus, and the infant.
Links to the abstract and further details can be found here: https://academic.oup.com/cid/article/65/suppl_2/S200/4589594#99553044
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